--- a/meson_post_install.py
+++ b/meson_post_install.py
@@ -19,4 +19,4 @@
 if len(sys.argv) > 1:
     print('Byte-compiling Python module...')
     python_source_install_path = sys.argv[1]
-    compile_dir(path.join(python_source_install_path, 'meld'), optimize=1)
+    compile_dir(path.join(environ.get('DESTDIR', '/'), python_source_install_path[1:], 'meld'), optimize=1)